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[BiodieselPlace]

What they said.
7.3 motor will tolerate good B100 and not so good batches of B100 (that's the key). I've had a 96 F250 7.3 for a few years making and running B100.

2 issues:

1- You will eventually need to changes the fuel rail hoses to a B100 resistant hose like Viton or an SAE 30R9 grade (fule injection grade hose). You can search this site, or others on the subject. I can help as well.

2- I have had to replace my fuel lift pump twice for leaks. I believe this is due to B100. Next time it leaks, I will make the change to electric pump system (airdog or the likes).

On the other hand, I have owned a 2006 6.0 and run B100 without any issues for 20K miles. They are much LESS tolerant of bad biodiesel (bio that has not been washed well or is not fully converted (not 100% reacted)). It will run just fine with ASTM grade B100.

It's ALL about the QUALITY of your biodiesel. Good quality B100 does not create any issues whatsoever in these motors. Make sure you test for conversion before your wash (so you can re-process it if needed) then check for soaps at the end to verify completeness of wash. Same applies for waterless washing. I personnaly water wash because it does a much better job at remove contaminants, residual glycerine, residual methanol, residual KOH (or NaOH) etc...

OK enough said...