On the driver's side head, towards the front, there is a sensor called the ICP--injector control pressure sensor.
It is stuck into the head at a 45 degree angle. If you disconnect the electrical connector and there is oil in it, that sensor is bad and needs to be replaced.
That may be the P1280. The P1211 may be related, but check that sensor first.
Your fuel leak is most likely your hard lines from your fuel bowl, there are rubber fittings that hold them in place . . .they just leak eventually.
The P0541 is your manifold air heater either shorted or opened, that won't cause any problems driving as it is disabled unless you're in park.
Oh, and this too:
http://www.superdutypsd.com/codes.php