The 5.25" speaker will fit directly in place of the stock front speakers. I'm not entirely sure about the size rear speakers, since I dont' have a crew cab and
Crutchfield's Website was of little help. My guess is also 5.25", but it's easy enough to pull the doors off and look.
Provided they fit, you will be able to run these aftermarket speakers with the stock head unit and wires. The stock head unit puts out ~8 rms watts/channel and your aftermarket speakers should be capable of 22 rms watts.
I would not suggest amping the factory stereo to run these. You'd have to use speaker-level inputs, and that general means noise. That also rules out the subs (for now), but it'll take you plenty of time/money to figure out where to mount these in the cab anyways.
Once you get a new head unit (with 3 pre-amp outputs), you run 3 RCA cables from the head unit to the respective amps (2 sets to the comp amp and 1 set to the sub amp). Then run the speaker wire from each amp.
Hope this helps,
-Rob
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2003 F-250 XLT 4x4 7.3L PSD SC LB 3.73L/S, Sonic Blue * Edge Juice, Attitude & Evolution * $15 AIC * LineX * Uniden PC68LTW CB * dual
blue 4' Firestik II * K&W toolbox *
blue interior lights* huskyliners (mud & floor) * Fumoto valve * Marinco block heater plug mod * heated & lighted tow mirrors
I have 2 articles on TDS, 1999+ $10/$15 AIC and Marinco mod block heater plug mod :
Photos and info