You might have a problem, as I dont think Ford engineered the frame flanges to handle the load from a 5th hitch. Most 5th hitches place the load on the side of the frame (by using brackets), not on the flange.
BUT... I have seen a kit from one of the hitch builders that had you mount the hitch to the frame flange, not to the side. I sent them all back after seeing the following:
(The folowing is is copied from the Ford body builders web site
https://www.fleet.ford.com/truckbbas...l/2000/275.PDF )
FRAME
1. Holes that would weaken the frame sidemember
should not be drilled in the frame. Holes are not to be
drilled in the sidemember’s top or bottom flange.
2. Holes to mount brackets, out-riggers and supports,
may be drilled in the vertical frame side rail web with
the following restrictions: .
Material between edge of hole and inside of upper
or lower flange must not be less than 1.50 inch for
low carbon steel (36,000 PSI yield).
The minimum edge distance between any two
holes up to 0.625 inch diameter must be 1.00 inch.
For larger than 0.625 inch diameter holes, the
minimum edge distance must be 1.5 times the
diameter of the largest hole.
0.75 inch is maximum hole diameter.
Avoid close vertical succession of fasteners.
All attaching fasteners, including flat washers,
must be of high strength steel (Grade 8).