It made a difference in my '04 f-250. I ran the diesel water wetter in that truck. I ran the same diesel water wetter in my '08 f-250. I'm getting ready to do a coolant flush - read up on it a little more - I'm going to put 2 bottles of the regular water wetter in this time. Apparently the diesel water wetter is meant for big rigs.
2008, F-250, FX4, Crew Cab, Short Bed, Oxford White w/ Black Interior, Dual Alternators, Sat. Navigation & Radio, Overhead DVD System, ESOF, Solid Rear Window, 3.73 Limited Slip, Upfitter Switches, Tow Command System w/ Power Scope Mirrors, Power Seats, and the Reverse Aid Sensor - Edge Insight Monitor, 2.5" Icon Lift Kit, Icon 2.5" Piggy-Back Shocks, KMC Beadlocks w/ 33" Toyo M/T's, MBRP DPF back exhaust, Recon mirror lights, Fitch Fuel Catalyst, Line-X, MotoBar, Gentex Temp/Direction Mirror, Baja Designs 22" Onx Pro Light Bar