Tires, and U-joints are the first things I would look at. I have several u-joints go over the years. Had a tire come apart last summer took out the driver side fender.
Early 1999 F350 AUTO 4x4 CC LB DRW 4.10 6.0 trans cooler, Front hitch, 2,000 hubs/ brakes, Bilstein shocks/steering stabilizer, Diesel site coolant filter 203 thermostat, EBV delete, new O-rings, new Oil cooler, RIFF RAFF FRX, Glow plug led, Pillar gauges, Lighted cupholder, Painless wiring fuze block, Harpoon/hutch mods, Removed axle blocks. Air bags, 5 wheel hitch, In bed 7 pin plug. Spare tire key delete. KLHANSEN on speed dial. 75,000 as of May 2019