'02 F250 New HPOP/IPR/ICP etc. Runs rough when hot..

First, never seen a scan tell you your injector is on its way out. Especially #8, it always fails. Boost leak is a good start. To be honest. I won't be giving any more advice on this one until you remove the Edge unit. No not un plugged. Harness right off the engine. 90% of the time I see an issue like this, its the Edge unit. They are prone to failure, mass numbers of them in both generations, and they cause all kinds of crazy engine related problems. My truck is the prime example. It was brought up from texas, totally stock except for an edge programmer. Beautiful truck real low mileage, no issues. Turns out the guy that brought it up here was selling because, yup you guessed it, it would run like crap when warm, and completely shut down for hours stranding him. He thought the truck was toast, and sold it to me real cheap. I removed the Edge that night. I drove that truck no issues for two years before I decided to do a power build. I then swindled Edge into replacing the unit with the new generation. THey did. Two months later. It packed it in and symptoms came back. Still have it sitting in a box if you know anyone who wants that junk. Take it off, drive without it. If its not the issue, we can go from there.