I have a buddy who has a 2001 F350, C/C 4X4, auto. He currently has 280,000 miles on it and all he has replaced is the ball joints and brakes. They abuse the hell out of that truck. The last 150,000 miles has basically been used as a hot shot truck for the company he works for (24ft trailer and 30ft gooseneck). The truck runs great, no tranny issues or weird noises (the injectors are quiet). The only performance mods he has done is ad an Edge Evo (80 HP mode), drop in oiled filter and exhaust. He has no gauges at all, even though I have told him about 50 times to get some. He just treats it like a truck, that must be the secret.