On one of my trucks, the original HPOP went to bits & puked metal into my injectors at 255k. When I pulled it out, the input "shaft" was sloppy & would bind as I turned it by hand. I posted about it here, got many reply's & nobody had ever seen one do that.
I had to have all the injector innards re-lapped & put an OEM replacement HPOP in as well as an IPR. At 288k, still running great.