Deleting the DPF and EGR coolers and running an appropriate tune will prolong the life of the engine. If you choose to go the route of crazy high HP racing tunes without doing many more mods on the engine (like ARP head Studs & other 'bullet proof' methods) then I think you are asking for trouble.
The "Best" is going to be subjective from each member. I can only speak of experience from what I use (in my sig below). For what you posted to be your primary concern (better mileage and performance), that little cute device will serve you very well.