A little more information regarding the various tuners from Banks.
The Six-Gun is plug and play, it mounts between the PCM and the drivetrain, intercepts the code from the PCM and rewrites it for the settings you have chosen. No need to remove the DPF and it gives you an additional 100 HP +/- a few. Mileage may gain you 1-2 or break even compared to stock. Even though the mileage numbers aren't huge, your not using additional fuel to make that extra HP. It's also the most DPF friendly tuner available. Since it comes after the PCM, it doesn't write information on the trucks computer so it makes it very easy to revert to stock in the need you have to pay a visit to the dealer. If you get the iQ with it, then you can monitor all the values and adjust things on the fly.
The AutoMind is also plug and play. You plug it into the OBD port and upload a new tune. This in a sense reprograms the trucks computer like the other tuners, more on that in a moment. Again, no need to remove the DPF and it gives you an additional 150HP +/- a few. Mileage on the SuperSport (highest) setting appears to be similar to the Economy setting of the Six-Gun with no noticeable increase in regens. From what I've seen so far, seems to be very DPF friendly like the Six-Gun above. Since this uploads tunes to the PCM like others, i.e Spartan, H&S, Superchips, etc.. it can possibly leave small footprints that could potentially be detected if someone actually goes looking for it. Probably not gonna happen though unless you have a major failure and need serious warranty work done. Supposedly, the Universal iQ version will allow you to monitor all the values that the truck is giving. Currently, I still have the Six-Gun installed on stock setting so am able to continue to use the iQ for monitoring so haven't verified or gone down that route yet.
The next version of the AutoMind is for offroad use only and does everything mentioned above but produces more power (250HP +/-), more mileage (values unknown) and requires you convert the truck to offroad use. In other words, it's not DPF friendly in any sense of the word. It's not available yet but they accidentally had the adds go out early on the back of the Diesel Power magazine, so the cat's out of the bag so-to-speak