Ford's E4OD and 4R100 on the Powerstrokes were specifically designed for towing in OD. Yes, previous to these trannies, towing in OD was considered taboo. I personally have seen several people in older gassers towing very small loads with OD and smoke their trannies.
However, if do too many go fast engine mods, you'll be back posting a different question, like, "How much does a new tranny cost?" Or like me--"Suncoast, MB, or BTS, who's the best bang for the buck?"