The tuner is needed to keep from throwing codes due to the deletes. You can run a stock power level tune, +40hp Tow, +80hp street, or +120hp Performance. I normally only run the stock and tow settings. Once the maxx is installed, you need to make some runs with the Performance settings so the transmission gets a head start on relearning.
I don't see the truck making best use of the Performance tune on a frequent basis unless you do some renovations and upgrades to the used engine parts.