I typically change my oil between 5,000 and 7,500 miles depending on what I am doing with the truck. Aside from fuel dilution (which you should not experience on the open road and towing), the oil holds up pretty well in these 6.7L engines. If you are short tripping the truck on a frequent basis, you will like have some moderate fuel dilution and that can be a good reason to change it early. I have UOA'ed a few of my samples and the ones where I was towing look really good even out to 7,500 miles. For information, I am only using xW-40 oils and have tried most of the majors (Rotella T6, Delo 400 LE, Mobil Delvac ESP1, & Kendall Super-DXa) and have had good luck with all of them--I especially liked the Mobil (5W-40 full synthetic) and the Kendall (15W-40 Synthetic Blend). I have also tried Delo XLE in 10W-30, but did not care for it.
Hope this helps!
Hope this helps!