I don't think they will. Do the mirror covers that you are talking about have the LEDs for turn signal and marker light in them? If so, then they will not work. If it some sort of an older cover thing then yes. The super duty mirrors on vans are the 99-03 F series style with an E series base. The newer mirrors on the 04-07 F series are the ones with the LEDs in them. The vans never got the newer type mirrors.